KISMAYU, Somalia, March 3 (Reuters) - Two missiles hit a makeshift house in a remote area of southern Somalia on Monday and local officials and witnesses said they believed it was a U.S. air strike against Islamist insurgents.

If confirmed, it would be at least the fourth U.S. air strike on Somalia in 14 months.

Residents of Dobley, a Somali town 220 km (140 miles) from the southern port city of Kismayu on the Kenyan border believe the missiles were targeting senior Islamist leaders meeting nearby.

"Two U.S missiles hit a house in Dobley early this morning," one local politician, who asked not to be named, told Reuters by telephone, adding that shrapnel from the missiles had been found.

"The town is very tense. People have started fleeing because they fear there might be more attacks."

The U.S. 5th Fleet in Bahrain and the Pentagon in Washington had no immediate information on the attack.

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