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Drug-resistant TB infects 500,000, WHO says
03 Jul 2007 20:51:18 GMT
Source: Reuters
July 3 (Reuters) - U.S. doctors treating a man who sparked international concern because he flew after being diagnosed with a dangerous form of tuberculosis said he in fact is infected with a somewhat milder form, multidrug-resistant TB, or MDR TB.

Here are some facts about MDR TB:

-- An estimated 500,000 people globally have MDR TB, according to the World Health Organization.

-- In MDR TB, the bacteria that cause the disease are resistant to the two most powerful anti-TB drugs, isoniazid and rifampicin.

-- MDR TB is called extensively drug-resistant TB or XDR TB if it also resists antibiotics in a class called fluoroquinolones, and at least one of three injectable second-line drugs -- capreomycin, kanamycin, and amikacin.

-- Only 70 percent of MDR TB cases are cured and only 30 to 40 percent of XDR TB cases can be cured.

-- WHO says there is probably no difference in the transmission of XDR-TB and any other forms of TB. The risk of becoming infected increases over time with contact.

-- Up to 90 percent of people infected with TB bacteria never develop TB disease, including those with MDR and XDR forms.

-- Symptoms of active disease include a cough with thick, cloudy mucus, sometimes with blood, for more than 2 weeks; fever, chills, and night sweats; fatigue and muscle weakness; weight loss; and in some cases shortness of breath and chest pain.
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Dr. Michel Kazatchkine (R), executive director The Global Fund to fight AIDS, Tuberculosis and Malaria (GFATM), and Deborah Landey, deputy executive director of UNAIDS, attend a news conference during the 8th International Congress on AIDS in Asia and the Pacific (ICAAP), in Colombo August 20, 2007. "The fight against AIDS cannot only be won by countries, it has to involve the civil societies, which has to involve the community affected by the disease. It has to get more and more involvement of the private sector," Kazatchkine told reporters on Monday.



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